Egaten  (triclabendazole)-  To treat fascioliasis, a parasitic infestation caused by two species of flatworms or trematodes that mainly the affect the liver, sometimes referred to as “liver flukes”.

EGATEN™ (triclabendazole) tablets, for oral use Initial U.S. Approval: 2019

 

Box of Egaten

EGATEN DOSAGE AND ADMINISTRATION

  • The recommended dose of EGATEN is 2 doses of 10 mg/kg given 12 hours apart in patients 6 years of age and older.
  • Take orally with food.
  • Swallow tablets whole or divide in half and take with water, or crush and administer with applesauce.
  • If the dosage cannot be adjusted exactly, round dose upwards.

 

EGATEN INDICATIONS AND USAGE

EGATEN™ tablet is an anthelmintic indicated for the treatment of fascioliasis in patients 6 years of age and older.

 

EGATEN ADVERSE REACTIONS

Most common adverse reactions (greater than 2%) with triclabendazole 20mg/kg dose are abdominal pain, hyperhidrosis, nausea, decreased appetite,
headache, urticaria, diarrhea, vomiting, musculoskeletal chest pain, and pruritus.

 

EGATEN DRUG INTERACTIONS

Re-check the plasma concentration of concomitantly administered CYP2C19 substrates after cessation of EGATEN therapy, if the plasma concentrations of the CYP2C19 substrates are elevated during administration of EGATEN.

 

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