Egaten (triclabendazole)- To treat fascioliasis, a parasitic infestation caused by two species of flatworms or trematodes that mainly the affect the liver, sometimes referred to as “liver flukes”.
EGATEN™ (triclabendazole) tablets, for oral use Initial U.S. Approval: 2019
EGATEN DOSAGE AND ADMINISTRATION
- The recommended dose of EGATEN is 2 doses of 10 mg/kg given 12 hours apart in patients 6 years of age and older.
- Take orally with food.
- Swallow tablets whole or divide in half and take with water, or crush and administer with applesauce.
- If the dosage cannot be adjusted exactly, round dose upwards.
EGATEN INDICATIONS AND USAGE
EGATEN™ tablet is an anthelmintic indicated for the treatment of fascioliasis in patients 6 years of age and older.
EGATEN ADVERSE REACTIONS
Most common adverse reactions (greater than 2%) with triclabendazole 20mg/kg dose are abdominal pain, hyperhidrosis, nausea, decreased appetite,
headache, urticaria, diarrhea, vomiting, musculoskeletal chest pain, and pruritus.
EGATEN DRUG INTERACTIONS
Re-check the plasma concentration of concomitantly administered CYP2C19 substrates after cessation of EGATEN therapy, if the plasma concentrations of the CYP2C19 substrates are elevated during administration of EGATEN.